Drug Delivery Based on Hydrogel for the Treatment of Cancer
DOI:
https://doi.org/10.22376/ijtos.v3i2.75Keywords:
Hydrogels, Controlled release, drug delivery system, Macroscopic design, microgels and nano gels, release mechanism, Drug diffusion coefficient, ApplicationsAbstract
This highlights the significance of controlled releasing biodegradable hydrogels as chemotherapeutic drug delivery systems. This study examines the use of hydrogels as drug delivery methods for HCC (Hepatocellular carcinoma), including thermo sensitive, pH-sensitive, photosensitive, dual sensitive, and glutathione responsive hydrogels. Localized chemotherapy, as opposed to systemic chemotherapy, can reduce side effects by delivering a steady supply of chemotherapeutic chemicals directly to the tumor location. Hydrogels have been used for wounds, burns, dressings, contact lenses, tissue engineering applications, and more. Finally, hydrogel can intelligently respond to environmental changes according to internal and external environmental stimuli, allowing for remote control and on-demand release of the anti-cancer active substance. This significantly improves drug targeting, lowering dosages and increasing treatment efficacy.
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