Rare Case of Oncocytic Carcinoma of Thyroid: Successful Surgical Management of a Large 20 Cm Tumor

Authors

  • Dr. Govindaraj Vardhanan Harshamitra Super Speciality Cancer Centre and Research Institute, Trichy, India.
  • Dr. Ponniah Sasipriya Harshamitra Super Speciality Cancer Centre and Research Institute, Trichy, India.
  • Dr. Gunasekaran Harshamitra Super Speciality Cancer Centre and Research Institute, Trichy, India.
  • Dr. A. Mallika Harshamitra Super Speciality Cancer Centre and Research Institute, Trichy, India.
  • Dr. Hareni Murugavel Harshamitra Super Speciality Cancer Centre and Research Institute, Trichy, India.

DOI:

https://doi.org/10.22376/ijtos.2025.3.1.48-51

Keywords:

Hürthle cell carcinoma, Oncocytic carcinoma, Thyroidectomy, Large tumor

Abstract

Oncocytic carcinoma of the thyroid (OTC), also known as Hürthle cell carcinoma (HCC), is an extremely rare diagnosis accounting for 3% to 5% of all thyroid cancers. Historically, Hürthle cell carcinoma was considered as a variant of follicular carcinoma because of its origin in the follicular epithelium. However, later reports suggested that they are more aggressive, and most cases were found to be refractory to Radioiodine ablation (RAI). The rarity of HCC and the historical overlap with follicular thyroid cancer has made it difficult to develop Hürthle cell carcinoma-specific management strategies. Management varies based on tumor size and extent, with total thyroidectomy being recommended for larger tumors. The role of radioactive iodine therapy remains controversial. In this report, we present a 71-year-old female who presented to our hospital with a massive (20 cm) thyroid tumor that was diagnosed as oncocytic carcinoma of the thyroid and was successfully managed with total thyroidectomy.

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Published

06-01-2025

How to Cite

Vardhanan, D. G., D. P. Sasipriya, Dr. Gunasekaran, D. A. Mallika, and D. H. Murugavel. “Rare Case of Oncocytic Carcinoma of Thyroid: Successful Surgical Management of a Large 20 Cm Tumor”. International Journal of Trends in OncoScience, vol. 3, no. 1, Jan. 2025, pp. 48-51, doi:10.22376/ijtos.2025.3.1.48-51.

Issue

Section

Case Study